The role of PCR in the diagnosis of tuberculous meningoencephalitis in children – Case report
نویسندگان
چکیده
Background Tuberculous (TB) meningoencephalitis is an extremely severe condition which requires a quick and correct diagnosis in order to institute a specific etiological treatment in a timely manner. The current “classical” diagnosis of TB meningitis is established through CSF cultures. The result is often inconclusive or is heavily delayed in the case of positive cultures (4-6 weeks). PLEX-ID is a new method which can establish an etiological diagnosis of bacterial infection in a matter of hours by detecting bacterial DNA in various pathological products (blood, CSF, synovial and pleural fluid).
منابع مشابه
Disseminated cutaneous Leishmaniasis with Tuberculous Dactylitis: A case report
Herein we report a 6-year-old Afghans patient referred to Department of Dermatology, St. AL-Zahra Hospital in Isfahan with ulcerative and nodular lesions disseminated over the face, arms, buttocks, pelvic girdle and legs in 2002. Direct smears of the lesions were positive for Leishman bodies. Leishmanin skin test was negative. He also had dactylitis in some digits and toes. PCR from bone biopsy...
متن کاملA Five Years Study of Tuberculous Meningitis in Iran
Background: Tuberculous meningitis (TBM) is a severe form of extra pulmonary tuberculosis with high mortality and morbidity rate in all age group patients specific in adults and children. The incidence and prevalence are not exactly known in Iran. In this study, we tried to evaluate the role of rapid diagnosis and to find out the highest risk group patients. Methods:Totally,...
متن کاملفراوانی عفونت سایتومگالو ویروس در مایع نخاع کودکان مبتلا به مننگوانسفالیت: روش PCR
Background: In recent years, many ill cases with cytomegalovirus reactivation in non-immuno compromised persons reported. Goal of study: to determine the CMV infection in cerebrospinal fluid of aseptic meningoencephalitis children hospitalized in Rasul & Mofid hospital (2005-2007). Methods: In a cross sectional study 132 cases selected with simple sampling. CMV-DNA in their Cerebro spinal flui...
متن کاملTuberculous Otitis Media Leading to Sequentialib Bilateral Facial Nerve Paralysis
Introduction: Tuberculous otitis media (TOM) is an uncommon, insidious, and frequently misdiagnosed form of tuberculosis (TB). In particular, TOM is usually secondary to direct transmission from adjacent organs, while the primary form has been rarely reported. The main aim of treatment is to start the patient on an antitubercular regime and early surgical intervention to decompress the facial n...
متن کاملTuberculoma (Case Report)
SUMMARY Tuberculoma of the central nervous system is one of the rare and unusual form of Tuberculous in Iranian children, that often present with mass lesion. This is report A 14 months old boy, admitted because ahd fever, irritability, anorexics had right side hemiplegia for two months. Positive finding was tuberculin test and CT brain scan with 2 hyperdenc mass (Ring Shaped) in the posto-m...
متن کامل